Both starters have fared well against each other in previous meetings, but have struggled in recent outings. Luis Castillo of the Reds has lost his last four starts while yielding 16 earned runs and six homers. Cubs starter Jose Quintana is winless in his last three outings and has struggled with control issues. Look for both lineups to have some success Friday and send this one Over the posted total.

Bettors have been attacking Cubs starter Jose Quintana’s strong road ERA, while Reds starter Luis Castillo had a strong home start against the Cubs on May 19. But he has struggled of late, and is particularly vulnerable to giving up home runs. Take the reverse angle here on the total and play the Over on Friday.