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White Sox vs. Yankees odds, line, picks: Proven model reveals MLB picks for May 21, 2022 matchup

SportsLine's projection model generated selections for Saturday's matchup between the Chicago White Sox and the New York Yankees
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The Chicago White Sox (19-19) and the New York Yankees (28-10) face off in the first contest of their three-game series on Saturday afternoon, with the first pitch set for 1:05 p.m. ET. New York is listed as the -215 favorite (risk $215 to win $100) at Caesars Sportsbook, while Chicago is set as the +185 underdog. The over-under for total runs expected is set at nine (see up-to-date odds for every game this week on our MLB odds page).

Before making any White Sox vs. Yankees picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a profitable start to the 2022 season. It's on a 33-25 roll on top-rated MLB money-line picks through six weeks, returning over $300 for $100 players. Anyone following it has seen HUGE returns!

The model knows Chicago shortstop Tim Anderson is a stout athlete with the quick hands and hips to turn on any pitch. Anderson has great speed on the bases with a terrific throwing arm. The 2021 All-Star is currently leading the team in batting average (.346), on-base percentage (.386), and hits (47). On May 19, he went 2-for-3 with two RBIs and one run scored. 

The model also knows New York right fielder Aaron Judge is a mammoth on the diamond with immense home-run power. Judge can unload on a pitch and drive it anywhere on the field with ease. The three-time All-Star is first on the team in batting average (.307), home runs (14), and hits (42). Judge is a big-time slugger in the lineup for New York with the ability to consistently produce. 

Now, it has set its sights on White Sox vs. Yankees. We can tell you the model is leaning Under the total, and it also says one side of the money line has ALL the value. You ABSOLUTELY need to see it before locking in any MLB picks.

So who wins White Sox vs. Yankees? And which side of the money line has ALL the value? Join SportsLine here to find out, all from the model that has crushed its top-rated MLB money-line picks!

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SportsLine Staff