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The United States men's national team looks to win its third international friendly match in a row when it battles Mexico on Saturday. The United States is coming off a 4-1 win over Peru on Sept. 26 and a 4-2 victory over Chile on Tuesday. Mexico, meanwhile, is coming off a pair of draws. Mexico played to a 1-1 draw with Colombia on Sept. 26 and a 1-1 draw with Peru on Tuesday. Mexico leads the all-time series 38-17-24.
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Kickoff is at 10 p.m. ET from State Farm Stadium in Glendale, Ariz. The latest United States vs. Mexico odds list the United States as the +145 favorites (risk $100 to win $145) on the 90-minute money line, with Mexico as the +180 underdogs. A draw is priced at +235, and the over/under for total goals is 2.5.
Before you lock in your United States vs. Mexico picks or make any international friendly predictions, you need to see what proven soccer expert Jon Eimer has to say.
Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Champions League, Serie A, the FA Cup, and more. He's been red-hot on his soccer betting picks in 2026, posting a 31-13-2 record and returning over $1,200 of profit on his Champions League picks. He also ended the World Cup on an 11-5-1 run and nailed seven of his past eight EPL spread picks! Anyone who follows him could be way up.
Now Eimer has turned his attention to the United States vs. Mexico match and we can tell you he is leaning Over 2.5 goals. He also has locked in two CONFIDENT best bets, one of which return plus-money, while offering a full breakdown of this international friendly matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own.
So where does all the betting value lie for United States vs. Mexico in the international friendly? ... Join SportsLine now to see Jon Eimer's picks for United States vs. Mexico, all from the insider who is on an 31-13 roll (+1200) on Champions League picks!
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Written by Daniel Kohn
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