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The United States men's national team looks to win their third international friendly match in a row when they battle Mexico on Saturday. The United States are coming off a 4-1 win over Peru on Sept. 26 and a 4-2 victory over Chile on Tuesday. Mexico, meanwhile, are coming off a pair of draws. Mexico played to a 1-1 draw with Colombia on Sept. 26 and a 1-1 draw with Peru on Tuesday. Mexico leads the all-time series 38-17-24. Claim the latest Polymarket promo code SPORTSLINE to get a $25 trading bonus after a $10 deposit:
Kickoff is at 10 p.m. ET from State Farm Stadium in Glendale, Ariz. The latest United States vs. Mexico odds list Mexico as the the +130 favorites (risk $100 to win $130) on the 90-minute money line, with the Americans as the +190 underdogs. A draw is priced at +290, and the over/under for total goals is 2.5.
Before locking in any United States vs. Mexico picks or predictions, you need to see what proven soccer expert Jon Eimer has to say.
Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Champions League, Serie A, the FA Cup, and more. He's been red-hot on his soccer betting picks in 2026, ending the World Cup on an 11-5-1 run! Anyone who follows him could be way up.
Now Eimer has turned his attention to the United States vs. Mexico match, and he is going Over 2.5 goals.
He also has locked in another CONFIDENT best bet that return plus-money, while offering a full breakdown of this international friendly matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own.
So where does all the betting value lie for United States vs. Mexico in the international friendly? ... Join SportsLine now to see Jon Eimer's picks for United States vs. Mexico, all from the insider who crushed his World Cup picks!
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Written by Daniel Kohn
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