Middleweights will top the bill at UFC Fight Night: Cannonier vs. Gastelum on Saturday, as veteran contenders Jared Cannonier takes on Kelvin Gastelum in the main event. The main UFC fight card from the UFC Apex in Las Vegas is set for 10 p.m. ET.

Cannonier (13-5) likes to strike early and has registered nine of his 13 wins via knockout. The 37-year-old began his MMA career in 2011 and went four years before suffering his first loss, a knockout to Shawn Jordan at UFC 182. He has gone 6-4 since and is third in the UFC middleweight rankings.

Gastelum has had a long and successful career, compiling a 16-7-1 record since his first fight in December of 2010. Like Cannonier, he started his career with a lot of success, winning his first 10 bouts. In April 2013, he defeated Uriah Hall by split decision to win the Ultimate Fighter 17 middleweight tournament. He has also fought at welterweight and catchweight.

Cannonier is a -155 favorite (risk $155 to win $100), while Gastelum is offered at +130 (risk $100 to win $130) in the latest UFC Fight Night: Cannonier vs. Gastelum odds at Caesars Sportsbook.

Before making any UFC Fight Night picks of your own, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past 30 months, $100 bettors who have followed Marley's picks are up more than $14,000. 

The accomplished MMA analyst has seen memorable run in 2020 carry over into 2021. He has now nailed 34 of his last 56 UFC main-event picks, a stretch that included a streak of five consecutive underdogs!

At UFC Fight Night last month, Marley's winners included calling a five-round decision victory for Sean Strickland (-210) against Uriah Hall (+190) in the middleweight main event. Anyone who has followed Marley is WAY UP! 

This week at UFC Fight Night: Cannonier vs. Gastelum, we can tell you Marley is backing Josiane Nunes (+125) to win by TKO over Bea Malecki (-150) in a matchup of women's bantamweight contenders.

Now, Marley has made the call on Cannonier vs. Gastelum and every other fight on the UFC Fight Night: Cannonier vs. Gastelum card. He's also backing one fighter to "dominate the early rounds" and pull off a submission victory! You ABSOLUTELY need to see Marley's other UFC Fight Night: Cannonier vs. Gastelum picks before making any of your own.

Who wins Cannonier vs. Gastelum and every bout on the UFC fight night card? And which fighter is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $14,000 on MMA picks!