Middleweight champion Dricus du Plessis defends his belt Saturday in the main event of UFC 312 in a rematch against top-rated former title-holder Sean Strickland.

Du Plessis is a -220 favorite (risk $220 to win $100), while Strickland is priced at +180 (risk $100 to win $180) in the latest MMA odds for UFC 312: du Plessis vs. Strickland 2. Before making any UFC 312 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In fact, he's up over $1,500 on his UFC main card picks!

His other highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card, and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him could be way up.

This week at UFC 312: du Plessis vs. Strickland 2, we can tell you Vithlani is picking Viacheslav Borschev (-115) to defeat Tom Nolan (-105) in a lightweight matchup on the preliminary card.

Vithlani has strong picks for du Plessis vs. Strickland and other bouts on the UFC 312 card. He's also backing a fighter whose "torrid pace" will be the deciding factor in a massive victory! You ABSOLUTELY need to see his UFC 312 picks before making any of your own!

Who wins du Plessis vs. Strickland, and which fighter is a MUST-BACK? Join SportsLine now to see which fighters you need to be all over, all from the expert who profited more than $1,500 on UFC main-card picks!