The American League Central-leading Minnesota Twins begin an eight-game road trip when they visit the division-rival Detroit Tigers on Monday afternoon for the opener of their five-game series. Minnesota (29-19) posted a 7-3 home victory against Kansas City on Sunday to earn a split of their four-game set. Detroit (17-29) edged Cleveland 2-1 at home for its third triumph in four contests and first series win since sweeping Baltimore two weeks ago. First pitch at Comerica Park is set for 1:10 p.m. ET.

Minnesota is listed as a -155 favorite (risk $155 to win $100) on the money line in the latest Twins vs. Tigers odds from Caesars Sportsbook, while the over-under for total runs scored is 8.5 (see the latest lines for every game on our MLB odds page).

Before making any Tigers vs. Twins picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

The model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through eight weeks, returning over $1,100 for $100 players. Anyone following it has seen HUGE returns!

The model knows Minnesota won the first five meetings between the teams this season before falling in 10 innings on Wednesday. The Twins flexed their muscles in Sunday's win against Kansas City as Gio Urshela, Nick Gordon and Trevor Larnach all homered, with the former's blast being a three-run shot in the third inning that gave the club a lead it wouldn't relinquish. Luis Arraez is among the top hitters in the major leagues with a .363 batting average after going 2-for-4 on Sunday.

The model also knows Detroit mustered only four hits in Sunday's triumph over Cleveland, but two were solo homers by Harold Castro and Jeimer Candelario. The duo recorded three blasts in the Tigers' 4-2 win at Minnesota on Wednesday, with Castro hitting a pair of solo shots and Candelario belting a decisive two-run homer in the 10th inning. The 28-year-old Castro has gone 7-for-11 over his last three contests.

Now, it has set its sights on Twins vs. Tigers. We can tell you the model is leaning Over on the total, and it also says one side of the money line has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Twins vs. Tigers? And which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the Tigers vs. Twins money line you should be all over on Monday, all from the model on a roll on MLB picks!