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No. 8 Alabama dismantled Florida State 50-36 last Saturday behind sophomore quarterback Keelon Russell, who threw for 320 yards in an impressive performance, and the Crimson Tide (3-0, 1-0 SEC) welcomed the South Carolina Gamecocks to Bryant-Denny Stadium on Saturday night. South Carolina comes in at 2-1 after a rough 41-34 home loss to Mississippi State last week despite 282 passing yards from junior quarterback LaNorris Sellers, who helped the Gamecocks open the season with blowout wins over Kent State and Towson before the SEC slate kicked off. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 7 p.m. ET at Bryant-Denny Stadium in Tuscaloosa, Alabama. The Crimson Tide are 12.5-point favorites in the latest South Carolina vs. Alabama odds, while the over/under is 53.5 points.
Before making any South Carolina vs. Alabama picks, check out the college football predictions from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times. It is off to a profitable 22-19 start on all top-rated college football picks so far this season, and it has been upgraded for the 2026 season to better factor in the transfer portal!
The model has simulated South Carolina vs. Alabama 10,000 times and the results are in. The model is going Under on the total, and it also says one side of the spread hits well over 60% of simulations!
So who wins South Carolina vs. Alabama, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is on a 22-19 run on top-rated CFB picks!
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