The Cincinnati Reds battle the Pittsburgh Pirates in the second of a four-game series between National League Central rivals on Friday. Pittsburgh is coming off a 7-0 win in Thursday's series opener. The Reds (60-56), who have dropped two in a row, are 27-30 on the road this season. The Pirates (50-66), who have won six of their past 10 games, are 33-27 on their home field in 2025.
First pitch from PNC Park in Pittsburgh is set for 6:40 p.m. ET. The Reds have won four of the past seven meetings with the Pirates. Cincinnati is a -124 favorite on the money line (risk $124 to win $100) in the latest Reds vs. Pirates odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 7.5 in the latest MLB odds.
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Written by Daniel Kohn
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