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Rangers vs. Orioles odds, line, start time, picks, best bets for June 22 American League matchup from proven model

SportsLine's projection model, which is on a 37-30 roll on top-rated MLB picks, has locked in its MLB picks for the Rangers vs. Orioles on Monday night

ByPublished: Jun 23, 2025 8:03PM UTC . 2 min read

Teams looking to get back on track meet when the Texas Rangers battle the Baltimore Orioles in a key American League matchup on Monday. The Rangers (38-40), who are third in the American League West, are 15-24 on the road this season. The Orioles (33-44), fifth in the American League East, are 16-19 on their home field in 2025.

First pitch from Oriole Park at Camden Yards in Baltimore is set for 6:35 p.m. ET. The Orioles have won five of the past seven meetings with the Rangers. Baltimore is a -130 favorite on the money line (risk $130 to win $100) in the latest Rangers vs. Orioles odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 9.5 in the latest MLB odds. 

Before you make any Rangers vs. Orioles picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 13 of the 2025 MLB season on a 37-30 run on top-rated MLB sides picks. It has excelled making home run prop picks, returning more than 35 units of profit over the past two months. Anybody following could have seen strong returns!

The model has simulated Rangers vs. Orioles 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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