Picking Every Game of the 2025 NFL Season: NFL season predictions, expert best bets
Eric Cohen reveals a winner for all 272 regular season NFL games, plus playoff predictions and best bets
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Is this the year the Buffalo Bills can get over their 30+ year Super Bowl drought? With arguably the most loyal fans in the NFL, the Bills continue to come up short of the Super Bowl in the most cruel ways. Last year, they entered the fourth quarter with a 1-point lead before losing by three to Patrick Mahomes and the Chiefs in Kansas City. With their roster largely intact from last season's 13-4 record, they have a chance to improve this season.
NFL preseason is now over with the 2025 NFL regular season starting on Thursday with Eagles vs. Cowboys (+8.5, 47.5) at 8:20 p.m. ET and a game in Brazil between the Chiefs and Chargers (+3, 45.5) on Friday at 8:15 p.m. ET. Which 2025 NFL win totals should you target, an which 2026 Super Bowl odds offer the best value?
Before you lock in any NFL picks or game predictions, you NEED to see what SportsLine NFL expert Eric Cohen has to say.
Cohen, SportsLine host of the weekly Early Edge NFL Props Show, is simulating the entire regular season and playoffs. Last year in his season picks article, Cohen hit three of four win totals best bets, two of four division winner best bets, and had the Eagles to win the NFC at +600. Anyone who followed Cohen's Best Bets was likely to be up big!
Now Cohen has found value in teams' win totals by simulating all 285 NFL games this season in an easy-to-read grid format.
We can tell you he is high on the Cincinnati Bengals to exceed their projected win total, saying they win 12 games. On the other hand, Cohen is fading the New Orleans Saints win total of 4.5 and expects them to be in the running for the first overall choice of the 2025 NFL Draft. In fact, Cohen says the Saints win just three games this season, including Week 12 against the Falcons.
Cohen is also high on a potential Super Bowl matchup that pays 65-1 and several win total bets at plus-money! You ABSOLUTELY need to see which NFL bets he's making before entering any of your own.
Which Super Bowl matchup would bring a HUGE payout of 65-1? Which NFL win totals should you back for all 32 teams, including several at plus-money? And which 2026 Super Bowl futures offer the best value? Join SportsLine now to get Eric Cohen's game-by-game NFL projections, all from the top expert who called the Eagles to win the NFC last year at 6-1 odds! ... You've unlocked our best deal! Get your first month of SportsLine for ONLY $1 with the promo code "LEAGUE"! Join here!
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