The San Diego Padres look to even their best-of-seven National League Championship Series when they take on the Philadelphia Phillies in Game 2 on Wednesday. The Phillies (87-75) defeated the Padres (89-73) 2-0 on Tuesday after Kyle Schwarber and Bryce Harper launched solo homers to lift Philadelphia. The Phillies are looking to reach their first World Series since 2009, while San Diego hasn't been to one since 1998. 

First pitch from Petco Park is set for 4:35 p.m. ET. San Diego is listed as a -120 favorite (risk $120 to win $100) on the money line in the latest Phillies vs. Padres odds from Caesars Sportsbook, while the over/under for total runs scored is 7. (see the latest lines for every game on our MLB odds page).

Before making any Phillies vs. Padres picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters the league championship round on a 20-13 roll on top-rated MLB money-line picks, returning more than $400. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen HUGE returns!

The model knows San Diego second baseman Jake Cronenworth was one of the reasons the Padres were able to get past the Dodgers. In the four-game series with Los Angeles, Cronenworth was 7-for-16 with a homer and five RBI. He has a history of postseason success, batting .389 in the 2020 playoffs with one triple, one homer and three RBI. During the regular season this year, Cronenworth batted .239 with 17 homers, 88 RBI and 88 runs scored.

The model also knows Philadelphia has a number of options on offense, including catcher J.T. Realmuto. Realmuto entered the series on a four-game hitting streak, going 5-for-18 (.278) in the four games against the Braves. He homered once and drove in a pair of runs. Realmuto has had his moments against the Padres throughout his career, with four doubles, three triples, eight homers and 23 RBI in 39 regular-season games against them.

Now, it has set its sights on Phillies vs. Padres. We can tell you the model is leaning Over on the total, and it also says one side of the money line has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Game 2 of Phillies vs. Padres? And which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the Phillies vs. Padres run line you should be all over on Wednesday, all from the model on a roll on MLB picks!