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The New England Patriots meet the Seattle Seahawks in a rematch from last year's Super Bowl game as the 2026 season kicks off on Wednesday night. Seattle, the defending Super Bowl champions, which won the NFC West with a 14-3 record, were 6-2 on its home field in 2025. New England, meanwhile, which won the AFC East with a 14-3 mark and reached the Super Bowl for the 12th time in team history, were 8-0 on the road last year. Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:
Kickoff is at 8:20 p.m. ET from Lumen Field in Seattle. The latest Patriots vs. Seahawks odds have Seattle as a 3-point favorite, while the over/under for total points scored is 44.5.
Before making any Patriots vs. Seahawks picks, or 2026 NFL Kickoff Game predictions of your own, you NEED to see what SportsLine expert Emory Hunt has to say.
Hunt is a CBS Sports HQ analyst who also is featured on SportsLine's Early Edge show breaking down NFL and CFB matchups. He enters this season on a 28-16 roll on picks involving the Seahawks, returning $1,047 to $100 players! Anyone following his picks could have seen huge returns.
Now, Hunt has locked in another confident pick for Patriots vs. Seahawks.
He's leaning Under the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.
So who wins Patriots vs. Seahawks on Wednesday, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine RIGHT NOW to see which side of the Patriots vs. Seahawks line to back, all from the expert who has returned $1,047 to $100 players in his last 44 picks involving the Seahawks!
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Written by Daniel Kohn
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