Patriots vs. Seahawks odds, line, time: Proven computer model reveals picks for 2026 NFL Kickoff Game

The Seattle Seahawks began their title defense against the team who they defeated in last year's Big Game as the champs host the New England Patriots in the 2026 NFL Kickoff Game on Wednesday. Sep 9. This is the second kickoff game to take place on a Wednesday, instead of the usual Thursday, since this tradition first began in 2002. Seattle is coming off a 14-3 regular season, which culminated in a 29-13 victory over the Pats in the Super Bowl. New England also went 14-3 in the regular season in Mike Vrabel's first year as head coach of the team.

Kickoff is set for 8:20 p.m. ET from Lumen Field in Seattle. The latest Seahawks vs. Patriots odds have Seattle as 3.5-point favorites, while the over/under for total points scored is 44.5.

Before making any Patriots vs. Seahawks picks or 2026 NFL Kickoff Game predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2026 NFL season on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Seahawks vs. Patriots in the NFL Kickoff Game 2026.

We can tell you it's leaning Over the point total. It also says that one side of the spread is hitting in well over 60% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Patriots vs. Seahawks in the 2026 NFL Kickoff Game, and which side of the spread hits well over 60% of the time? ... Join SportsLine RIGHT NOW to see which side of the Seahawks vs. Patriots line to back, all from the model that is on a 53-37 run on top-rated picks since 2024!