The No. 6 Oregon Ducks will be looking to stay unbeaten when they host the Michigan State Spartans on Friday night. Oregon is coming off back-to-back blowout wins, including a 34-13 win at UCLA last week. Michigan State is hoping to bounce back from a 38-7 loss against No. 3 Ohio State. 

Kickoff is set for 9 p.m. ET on Friday at Autzen Stadium. Oregon is favored by 23.5 points in the latest Oregon vs. Michigan State odds, while the over/under is 52 points, per SportsLine consensus. Before entering any Michigan State vs. Oregon picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread.  It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen STRONG returns.

The model has simulated Oregon vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in 60% of simulations!

So who wins Oregon vs. Michigan State, and which side of the spread hits 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!