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A Big Ten matchup in the Week 10 college football schedule has the No. 11 Ohio State Buckeyes hosting the Oregon Ducks on CBS and Paramount+. The Buckeyes (6-2, 4-1 Big Ten) saw a five-game win streak come to an end at the hands of USC on Saturday, while the Ducks (5-3, 3-2 Big Ten) are coming off an upset of then-No. 20 Northwestern in Week 9. Both teams have seen their starting quarterbacks sidelined, with Julian Sayin out for Ohio State and Dante Moore injured for Oregon. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Kickoff is at 3:30 p.m. ET from Ohio Stadium in Columbus, Ohio. The Buckeyes are 7.5-point favorites in the latest Oregon vs. Ohio State odds. The over/under for total points is 46.5. Before making any Ohio State vs. Oregon picks, check out the college football predictions from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times. It entered Week 10 with an 80-77 record on all top-rated college football picks this season.
The model has simulated Oregon vs. Ohio State 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits in over 60% of simulations.
So who wins Ohio State vs. Oregon, and which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the Oregon vs. Ohio State spread you need to jump on, all from the computer model that simulates every game 10,000 times!
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Written by Ross Kelly
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