An ACC battle has the Clemson Tigers (19-5) hosting the North Carolina Tar Heels (14-10) Monday. The Tigers are coming off a big-time upset win Saturday, beating No. 2 Duke 77-71. North Carolina is also fresh off a win Saturday, edging out Pittsburgh 67-66. 

Tipoff is scheduled for 7 p.m. ET at Littlejohn Coliseum in Clemson, SC. The Tigers are 4.5-point favorites in the latest North Carolina vs. Clemson odds from SportsLine consensus, while the over/under for total points scored is 144.5.

Before entering any UNC vs. Clemson picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 15 of the 2024-25 season on a 211-154 roll (+2024) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated North Carolina vs. Clemson 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins North Carolina vs. Clemson, and which side of the spread hits in nearly 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!