Not all NFL rivalries have to be divisional ones, and the Week 6 NFL schedule provides matchups with ties that bind respective teams. Ravens vs. Commanders (+6.5, 51.5) is a regional rivalry in the DMV, as Baltimore will host Washington for the first time since 2016. Steelers vs. Raiders has Pittsburgh as a 3-point favorite in the Week 6 NFL spreads, after these two met in the playoffs for five straight years (1972-76), which is a record. Finally, there's Cowboys vs. Lions (-3, 52.5), which features the two annual Thanksgiving Day hosts whose contest last year ended in controversial fashion involving an ineligible lineman.

You'll also have to monitor plenty of NFL injuries this week, including Saints quarterback Derek Carr, who has been ruled out with an oblique injury. Before you lock in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 6 of the 2024 NFL season, and the results are in.

We can tell you one of the model's strongest Week 6 NFL picks is that the Falcons (-6, 46.5) cover the spread versus the Panthers. Atlanta wins by a touchdown and an extra points and the model says the Falcons are the stronger value. Another one of its Week 6 NFL predictions: the Commanders (+6.5, 51.5) cover on the road versus the Ravens over 50% of the time. The model also says the Over hits in well over 50% of simulations.

The model has also made the call on who wins and covers in every other NFL game this week and just revealed TWO UNDERDOGS that win outright! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 6, and which two underdogs should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 191-131 roll on top-rated NFL picks!