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When it comes to Week 2 NFL bets that return plus money, many will first think of backing underdogs on the money line with their NFL predictions. However, a Week 2 NFL parlay could be composed of several other types of longshot picks with notable payouts, from NFL props on touchdown scorers to predicting winning margins. An example of the latter could be utilized in the Seahawks vs. Cardinals game, as Seattle's defeated Arizona by exactly 10 points in four of their last eight meetings. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
The Seahawks winning on Sunday by 7-12 points would return +400, while the alternate NFL spread of Seattle (-9.5) has a +174 payout. Those could be standalone picks or individual parlay legs as part of your Week 2 NFL betting strategy.
Before making your Week 2 NFL picks and parlays, you NEED to see the Week 2 longshot NFL parlay from SportsLine's proven computer simulation model that could return almost $1.6 million for a $10 bettor.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
For Week 2, one of the picks in the six-leg longshot parlay is backing both teams to score 25+ points in Cowboys vs. Commanders on Sunday at 4:25 p.m. ET. The model projects a final score of 32-28.
The parlay also includes other picks from the SportsLine computer model, including multiple touchdown scorer props that return over +1200! You ABSOLUTELY need to see these picks before locking in any NFL picks of your own.
What are the top NFL picks for Week 2 that can be combined into a parlay that returns almost $1.6 million for $10 bettors? ... Join SportsLine now to see the top NFL picks this week and best bets from SportsLine's proven computer simulation model, and find out!
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Written by Ross Kelly
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