The 2023 Week 3 NFL schedule opens with a high-profile Thursday Night Football matchup when Brock Purdy and the San Francisco 49ers host Daniel Jones and the New York Giants. Kickoff is at 8:15 p.m. ET. In an NFL DFS player pool that features several high-end fantasy options like Christian McCaffrey, Deebo Samuel, George Kittle, and Darren Waller, there will be tough decisions to be made when building NFL DFS lineups. Should Purdy or Jones be part of your Thursday Night Football DFS lineups or NFL DFS stacks?

Before locking in any playoff NFL DFS lineups or NFL DFS stacks for Giants vs. 49ers on Thursday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

In the Week 2 Eagles vs. Vikings Thursday Night Football matchup Kaylor was all over Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), and T.J. Hockenson (7-66-2). Anyone who followed his picks cashed in BIG.

Now, Kaylor has turned his attention to 49ers vs. Giants on Thursday Night Football in Week 3 and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Thursday Night Football is 49ers running back Christian McCaffrey. "Christian McCaffrey is off to a blazing start to the 2023 season and seems to be fully comfortable in Kyle Shanahan's offense. He leads the league in rushing yards by a fairly wide margin, and appears to have a floor of 20 touches per game going forward" Kaylor told SportsLine. Part of Kaylor's optimal NFL DFS strategy also includes rostering Giants tight end Darren Waller, who should see an increase in targets with Saquon Barkley out for this contest. 

Kaylor is also targeting another under-the-radar player for TNF who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

What are the top NFL DFS picks for TNF, and which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a DFS expert who won a prestigious Millionaire Maker tournament!