The 2023 Week 16 NFL schedule opens with a Thursday Night Football matchup between the New Orleans Saints and Los Angeles Rams. Kickoff is at 8:15 p.m. ET at SoFi Stadium. In a game where both teams are looking to keep their postseason hopes alive, finding the top values in the NFL DFS player pool when building your NFL DFS lineups will require shrewd decision-making. The over/under for total points scored is set at 45 points, down from 46.5, in the latest Rams vs. Saints odds.

Who should be included in your TNF NFL DFS picks and NFL DFS stacks? and which players should you fade? Before locking in any NFL DFS lineups or NFL DFS stacks for Saints vs. Rams on Thursday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

This year, Kaylor has been all over players like Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), T.J. Hockenson (7-66-2), D.J. Moore (8-230-3), David Montgomery (121-3), Ja'Marr Chase (12-141, 11-149-1), Alvin Kamara (12-91, 76), Jordan Addison (7-123-2), Jahmyr Gibbs (152-1, 5-37), Javonte Williams (79, 3-31-1), Dak Prescott (331-4), CeeDee Lamb (12-116-1), DK Metcalf (6-143-3), and Aidan O'Connell (248-4) in single-game slates. Anyone who followed his picks cashed in BIG!

Now, Kaylor has turned his attention to Rams vs. Saints on Thursday Night Football in Week 16 and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Thursday Night Football is Rams quarterback Matthew Stafford. Part of Kaylor's optimal NFL DFS strategy also includes rostering Saints running back Alvin Kamara, who remains one of the top all-purpose backs in the NFL.

Kaylor is also targeting another under-the-radar player for TNF who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about rosters changes/updates

What are the top NFL DFS picks for Saints vs. Rams on Thursday Night Football, and which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a DFS expert who won a prestigious Millionaire Maker tournament!