Two of the best teams in baseball collide when the Houston Astros take on the New York Mets in the first game of a two-game series on Tuesday at Citi Field in Queens. The Mets (47-27) lead the NL East and have the second best record in baseball. Meanwhile the Astros (45-27) lead the AL West and are tied for the third best record in the majors.

Houston is a -125 favorite in the latest Astros vs. Mets odds from Caesars Sportsbook while New York is a +105 underdog. First pitch is set for 7:10 p.m. ET. The game is one of 16 on the MLB schedule for Tuesday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and is off to a strong start to the 2022 season. The model is on a 59-51 run on top-rated MLB money-line picks through 12 weeks. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series last season. Anybody who has followed the model has seen profitable returns.

Now, the model has set its sights on the MLB schedule for Tuesday, June 28. Using its top picks for the day, the model has generated a four-leg parlay that would pay almost 13-1! The parlay doesn't start until 8 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the White Sox (+110) to beat the Angels. But the model has three other picks, including a play on an even bigger American League underdog! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which American League underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of almost 13-1? ... Join SportsLine right now to find out which picks you should be all over on Tuesday, all from the model that is on a 59-51 roll on top-rated MLB money-line picks through 12 weeks!