The surging Arizona Diamondbacks host the Boston Red Sox on Friday to kick off a three-game weekend series. First pitch is set for 9:40 p.m. ET from Chase Field.

The Red Sox are -140 favorites (risk $140 to win $100), while the Diamondbacks return a price of +118 in the latest Caesars Sportsbook MLB odds. The over/under for total runs scored is 8.5. (See up-to-date lines for every game on our MLB odds page.) That game is one of 15 on the Friday MLB schedule. 

Before making any MLB picks or parlays for Friday's games, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It has opened the 2023 MLB season on a 26-17 roll (+379) on all top-rated MLB picks. Anybody who has followed it has seen profitable returns!  

Now, the model has set its sights on the MLB schedule for Friday and has generated a three-leg parlay that would pay nearly 71! The parlay doesn't start until 8:10 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the Seattle Mariners (-155) over the Pittsburgh Pirates (10:10 p.m. ET). But the model also has two other picks, including one underdog play! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of nearly 7-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is on a 26-17 run on top-rated money-line picks!