MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Friday, May 15, from a daily Fantasy pro

Rivalry weekend kicks off in Major League Baseball with a 15-game slate, which begins at 6:40 p.m. ET, with the last first pitch set for 9:40 p.m. ET. Among the top options in the MLB DFS player pool include Blake Snell, Spencer Strider, Cam Schlittler, Ketel Marte, Bobby Witt Jr., Corbin Carroll, Yordan Alvarez, Elly De La Cruz, Aaron Judge, Rafael Devers, Ian Happ, Pete Crow-Armstrong, Freddie Freeman, Kyle Tucker and Max Muncy. Among those not available and on the injured list include Carlos Santana (groin), Ronald Acuna Jr. (hamstring), Ryan Mountcastle (foot), Roman Anthony (wrist), Eugenio Suarez (oblique), Carlos Correa (ankle), Jonathan India (shoulder), Tyler Glasnow (back), Joey Bart (foot), Cal Raleigh (side) and Luis Robert Jr. (back).

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Friday, one of McClure's top MLB DFS picks is Arizona second baseman Ketel Marte ($5,700 DraftKings, 3,600 FanDuel). He's also building around Arizona catcher Gabriel Moreno ($3,700 DraftKings, $3,100 FanDuel). He had two hits in Wednesday's 6-5 loss to the Texas Rangers. He is a career .277 hitter and is coming off a season in which he batted .285 with 12 doubles, one triple, nine homers and 40 RBI in 83 games.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Friday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!