MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Friday, June 12 from a daily Fantasy pro

A full-slate of 15 games highlights Friday's Major League Baseball schedule, which begins at 6:40 p.m. ET, with the last first pitch set for 10:15 p.m. ET. Among the top options in the MLB DFS player pool include Jacob Misiorowski, Joe Ryan, Sonny Gray, Nick Kurtz, Byron Buxton, Bobby Witt Jr., Jackson Chourio, Brice Turang, Jose Ramirez, Yandy Diaz, Andy Pages, Sal Stewart, Corbin Carroll and Kyle Schwarber. 

With only so much MLB DFS salary cap space, you'll have to be judicious on who you select to compose your daily Fantasy baseball lineups.

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Friday, one of McClure's top MLB DFS picks is Houston DH Yordan Alvarez ($6,200 DraftKings, $4,400 FanDuel). He's stacking him Houston third baseman Isaac Paredes ($3,700 DraftKings, $3,000 FanDuel). Paredes has a .250 career batting average against Kansas City Royals pitchers. He has hits in five of his last eight games, including a 2-for-3 performance with a double and an RBI in a 13-2 win over the Athletics on Saturday.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Friday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!