MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Friday, April 24, from a daily Fantasy pro

Friday's Major League Baseball schedule features 14 games, beginning at 6:40 p.m. ET, with the last first pitch set for 10:15 p.m. ET. Among the top options in the MLB DFS player pool include Freddy Peralta, Paul Skenes, Brandon Woodruff, Aaron Judge, Shohei Ohtani, Juan Soto, Bobby Witt Jr., Julio Rodriguez, Matt Olson and Kyle Tucker. Among those not available and on the injured list include Ryan Mountcastle (foot), Jackson Holiday (finger), Roman Anthony (back), Taylor Trammell (groin), Christian Yelich (groin), Jackson Chourio (hand), Anthony Volpe (shoulder) and Mookie Betts (back).

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Friday, one of McClure's top MLB DFS picks is Texas Rangers first baseman Joc Pederson ($2,700 DraftKings, $2,500 FanDuel). He's also building around Kansas City Royals outfielder Lane Thomas ($2,000 DraftKings, $2,300 FanDuel). He has hits in six of the past eight games. In 620 career games, he is batting .241 with 108 doubles, 11 triples, 76 homers and 256 RBI.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Friday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!