The 18th-ranked Kentucky Wildcats look to start off their SEC schedule on a high note when they battle the Missouri Tigers on Wednesday night. The Wildcats (9-2) are 13-2 all-time against Missouri, while the Tigers (6-6) are 3-6 all-time in SEC openers. Tipoff from Rupp Arena in Lexington, Ky., is set for 7 p.m. ET. Kentucky is favored by 20 points at Caesars Sportsbook, while the over-under for total points is set at 140 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Missouri vs. Kentucky picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows the Wildcats are led by reigning USBWA National Player of the Week and Co-SEC Player of the Week Oscar Tshiebwe. The junior forward leads the nation in rebounds per game (15.5) and set a Rupp Arena record with 28 rebounds in last week's 95-60 win over Western Kentucky. Tshiebwe has double-figure rebounds in all but one game. He also has a team-best 16.1 scoring average and has registered nine double-doubles.

The model also knows the Tigers enter the game with six players averaging eight points per game or better, led by junior forward Kobe Brown, who is averaging 14.8 points per game. Brown had a career-high 27 points in an 83-75 win over Utah on Dec. 18, and is tied for second in the SEC with four 20-plus point games this year. Brown recorded three consecutive double-doubles from Nov. 29 to Dec. 7, making him the first Missouri player to do so since Demarre Carroll in 2009. Brown is the third-leading rebounder in the conference, averaging 8.9 per game, and also ranks third in field goal percentage (52.9) and ninth in scoring.

Now, it has set its sights on Missouri vs. Kentucky. It is leaning Over on the total and it also says one side of the spread hits in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Missouri vs. Kentucky? And which side of the spread hits in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Missouri vs. Kentucky spread you should be all over Wednesday, all from the model on a roll on college basketball picks!