The Memphis Tigers will take on the Colorado State Rams in a West Region matchup in the first round of the 2025 NCAA Tournament on Friday. Memphis (29-5) landed the No. 5 seed in the West, while Colorado State (25-9) earned the No. 12 seed. The Tigers, led by head coach Penny Hardaway, posted a 16-2 record in American Athletic Conference play. The Rams went 16-4 in the Mountain West before going on a run to win the conference tournament championship. CSU is 21-13 and Memphis is 16-18 against the spread this season.
Tipoff from Intrust Climate Pledge Arena in Seattle, Washington, is set for 2 p.m. ET. Colorado State is a 1.5-point favorite in the latest Colorado State vs. Memphis odds from SportsLine consensus, while the over/under for total points scored is 146.5.
Before making any Colorado State vs. Memphis picks, check out the college basketball predictions from the SportsLine Projection Model.
The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!
The model has simulated Colorado State vs. Memphis 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in well over 60% of simulations!
So who wins Colorado State vs. Memphis in the 2025 NCAA Tournament, and which side of the spread hits in well over 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!
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