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The Detroit Lions will look to make it two wins in a row when they clash with the Carolina Panthers in a key NFC matchup on Sunday Night Football. Detroit held off the New York Jets 31-24 in Week 3, while Carolina dropped a 21-18 decision to the Cleveland Browns. The Lions (2-1), who tied for third in the division at 9-8 in 2025, are 0-1 on the road this season. The Panthers (1-2), who won the NFC South with an 8-9 mark last year, are 0-1 on their home field in 2026. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 8:20 p.m. ET from Bank of America Stadium in Charlotte, N.C. The latest Lions vs. Panthers odds have Detroit as 3.5-point favorites. The over/under for total points scored is 50.5. Both teams are 1-2 against the spread this season.
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Written by Daniel Kohn
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