Knicks vs. 76ers odds, line: Proven model reveals picks for NBA Eastern Conference semifinal Game 3 matchup on Friday, May 8

Joel Embiid was a surprise scratch in Game 2 of the NBA Playoffs second-round series between the Philadelphia 76ers and New York Knicks. The Knicks won the game 108-102 but the Sixers hung strong without their star center. Embiid is questionable on Friday night as the best-of-7 series heads to Philly for Game 3. The Sixers went 2-0 at home vs. the Knicks in the regular season. 

Tipoff from Xfinity Mobile Arena in Philadelphia is set for 7 p.m. ET as the 76ers, the No. 7 seed in the East, aim to bounce back and avoid a 3-0 deficit. Philadelphia is at -1.5 in the latest Knicks vs. 76ers odds from FanDuel Sportsbook, while the over/under for total points scored is 213.5. 

Before making any Knicks vs. 76ers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the second round of the 2026 NBA playoffs on a sizzling 26-9 roll (74%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Knicks vs. 76ers 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits nearly 70% of the time!

Who wins 76ers vs. Knicks, and which side of the spread hits nearly 70% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 26-9 roll on top-rated NBA picks!