The Vanderbilt Commodores will try to pick up another big upset when they go on the road to face the Kentucky Wildcats on Saturday night. Vanderbilt is coming off the biggest win in school history, taking down then-No. 1 Alabama last week. Kentucky is coming off an upset of its own, beating then-No. 6 Ole Miss as a 17.5-point underdog two weeks ago.  

Kickoff is set for 7:45 p.m. ET on Saturday at Kroger Field. Kentucky is favored by 13.5 points in the latest Kentucky vs. Vanderbilt odds, while the over/under is 44.5 points, per SportsLine consensus. Before entering any Vanderbilt vs. Kentucky picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks since inception, and is 8-4 on top-rated picks over the past two weeks of this season. Anyone who has followed it has seen strong returns.

The model has simulated Kentucky vs. Vanderbilt 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60% of simulations!

So who wins Kentucky vs. Vanderbilt, and which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!