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Kentucky vs. South Carolina odds, line, spread: Proven model reveals college football picks, predictions for Week 6, 2022

SportsLine's projection model generated CFB picks, predictions, and best bets for South Carolina Gamecocks vs. Kentucky Wildcats
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An SEC battle is on tap between the Kentucky Wildcats and the South Carolina Gamecocks at 7:30 p.m. ET on Saturday at Kroger Field. UK is 4-1 overall and 3-0 at home, while USC is 3-2 overall and 0-1 on the road. The Wildcats are ranked third in the East Division; the Gamecocks are ranked fourth. 

The Wildcats are favored by 10.5 points in the latest Kentucky vs. South Carolina odds from Caesars Sportsbook, and the over/under is set at 49. Before you make any South Carolina vs. Kentucky picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Kentucky vs. South Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Kentucky vs. South Carolina? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!

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SportsLine Staff

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