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Kentucky will host James Madison on Friday night at Rupp Arena, looking to stay unbeaten after a dominant 85-57 win over Manhattan on Tuesday. No. 23 Kentucky (1-0) got 24 points from Milan Momcilovic in their opener and enter as 25.5-point favorites against a Dukes team off to a 0-1 start after falling to Miami (OH) 86-77. James Madison forward Paul Jones III leads the Dukes with 14.0 points per game, but the Wildcats bring depth and home-court advantage in what projects to be a lopsided non-conference affair in Lexington. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Tipoff from Rupp Arena at Central Bank Center in Lexington is at 7 p.m. ET. Kentucky is a 25.5-point favorite in the latest James Madison vs. Kentucky odds, while the over/under is 157.5.
Before making any James Madison vs. Kentucky picks, you NEED to see which side the SportsLine projection model is on.
The SportsLine Projection Model simulates every college basketball game 10,000 times. It enters the 2026-27 season on an 11-1 run on its top-rated over/under college basketball picks dating back to 2025, and is on a 28-22 run on top-rated CBB side picks. Anybody following has seen strong returns!
Now, the model has locked in another confident pick for James Madison vs. Vanderbilt in the college basketball Week 1 2026 matchup.
The model is going Under the point total. It also says that one side of the spread hits well over 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.
Who wins James Madison vs. Vanderbilt, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on an 11-1 run since 2025 on CBB picks!
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