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Teams looking to get back into the win column clash when the Duke Blue Devils battle the Virginia Cavaliers in a key Atlantic Coast Conference matchup on Friday night. Duke is coming off a 24-20 loss to North Carolina, while Virginia dropped a 23-13 decision at SMU on Saturday. The Blue Devils (4-2, 1-2 ACC), who are tied for 11th in the conference, are 1-1 on the road this season. The Cavaliers (4-3, 2-2 ACC), who are tied for fourth in the league, are 1-1 on their home field in 2026. Virginia leads the all-time series 42-35, but Duke won the ACC Championship Game 27-20 in overtime over the Cavaliers last December. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Kickoff is set for 7 p.m. ET at David A. Harrison III Field at Scott Stadium in Charlottesville, Va. The Cavaliers are 1.5-point favorites, with the over/under at 47.5 in the latest Duke vs. Virginia odds.
Before making any Duke vs. Virginia picks, check out the college football predictions from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times. It entered Week 8 on a 59-49 run on all top-rated college football picks, returning nearly $600 for $100 players. Anybody following could have seen strong returns!
The model has simulated Duke vs. Virginia 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits in over 50% of simulations!
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Written by Daniel Kohn
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