Cross-town rivals clash when the Chicago Cubs (18-26) travel to play the Chicago White Sox (22-22) on Saturday evening, with the first pitch set for 7:15 p.m. ET. The White Sox are listed as the -140 favorites (risk $140 to win $100) at Caesars Sportsbook, while the Cubs are set as the +120 underdogs. The over-under for total runs expected is set at eight (see up-to-date odds for every game this week on our MLB odds page).

Before making any Cubs vs. White Sox picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 41-30 roll on top-rated MLB money-line picks through seven weeks, returning almost $600 for $100 players. Anyone following it has seen HUGE returns!

The model knows White Sox shortstop Tim Anderson is a nice versatile piece. Anderson owns terrific speed on the field and is a threat to steal a few bases. The 2021 All-Star has been a force at the plate, consistently making contact with the ball. He currently ranks second in the MLB in batting average (.363) with five homers and 19 RBIs. In his last outing, he went 3-for-5 with three singles and one run scored.

The model also knows Cubs center fielder Ian Happ is a pure hitter with quick hands to turn on a pitch he likes. Happ adds versatility to Chicago's defense with the ability to both in the outfield and the infield. The 27-year-old leads the team in batting average (.275), RBIs (25), and hits (38). He's recorded a hit in three of his last five games. 

Now, it has set its sights on Cubs vs. White Sox. We can tell you the model is leaning Over the total, and it also says one side of the money line has ALL the value. You ABSOLUTELY need to see it before locking in any MLB picks.

So who wins Cubs vs. White Sox? And which side of the money line has ALL the value? Join SportsLine here to find out, all from the model that has crushed its top-rated MLB money-line picks!