Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you.
loading...
loading...
Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you.
The Kansas City Chiefs will look to make it two primetime wins in a row when they battle the Indianapolis Colts on 'Sunday Night Football.' Kansas City opened the regular season with a 31-10 thrashing of the Denver Broncos on Monday night, while Indianapolis dropped a 41-23 decision to the Baltimore Ravens this past Sunday. The Colts (0-1), who finished third in the AFC South at 8-9 a year ago, have lost eight consecutive games dating back to last season. The Chiefs (1-0), who finished third in the AFC West at 6-11, are looking to reach the postseason for the 11th time in 12 years. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 8:20 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City, Mo. The Chiefs won the last meeting in November 2025. The latest Colts vs. Chiefs odds have Kansas City as 5.5-point favorites, while the over/under for total points scored is 45.5. Indy is 8-8-2 against the spread since the start of last season, with Kansas City at 7-10-1 ATS.
Before making any Colts vs. Chiefs picks or 2026 NFL Week 2 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
Now, the model has locked in another confident pick for Colts vs. Chiefs in the NFL Week 2 2026 'Sunday Night Football' matchup.
We can tell you it's leaning Over the point total. It also says that one side of the spread is hitting in more than 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.
So who wins Colts vs. Chiefs in the 2026 Week 2 matchup, and which side of the spread hits more than 50% of the time? ... Join SportsLine RIGHT NOW to see which side of the Colts vs. Chiefs line to back, all from the model that is on a 53-39 run on top-rated picks since 2024!
Don't miss out: All new SportsLine memberships include Paramount+ Premium -- a $13.99/month value -- for no extra cost! Join now and get it all.
GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!
Written by Daniel Kohn
View expert profile