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The Week 3 college football schedule features at least one game on Thursday, Friday and Saturday. One of the juiciest storyline games of the year unfolds on Saturday as Ole Miss hosts Lane Kiffin and LSU in a top-10 matchup. The atmosphere in Oxford should be raucous as Kiffin returns to the program he bolted from before last season's College Football Playoff began. Kiffin's Tigers are 3-point favorites in the latest Week 3 college football odds. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Our proven computer model has revealed exact score predictions for each game that can help you formulate spread, money-line and over/under under picks.
Before making any college football picks for those games or others in Week 3, be sure to see them all.
The model simulates every FBS game 10,000 times. It is on a 33-21 run on top-rated CFB money-line picks since the 2024 season, and it has been upgraded for the 2026 season to even better factor in the transfer portal!
Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 3 game, and the exact score projections are in.
One of the score projections from the model in Week 3: Alabama beats Florida State 33-20, but it is FSU (+20.5) that covers well over 60% of the time. The Over (49.5), meanwhile, hits in well over 50% of sims.
The model has also made the exact call on the score for every other game, and it's calling for multiple underdogs to win outright, including an upset in one of the week's biggest matchups!
So what is the exact score prediction for each Week 3 game, and which underdog pulls off a shocking upset? ... Join SportsLine now to see who wins and covers every single game, all from the model that is on a 33-21 run on top-rated money line picks since 2024!
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