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College football score predictions: Picks for Week 2, 2026 from proven model

The SportsLine Projection Model, which is on a 33-20 run on top-rated CFB money line picks, has revealed its Week 2 college football score predictions

ByDaniel Lewis
·Updated: Sep 08, 2026 12:45PM ET·2 min read
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The Week 2 college football schedule features one FBS vs. FCS matchup on Thursday -- Miami vs. Florida A&M -- and then continues on both Friday and Saturday. The weekend is anchored by a couple huge non-conference matchups on Saturday: No. 10 Oklahoma vs. No. 16 Michigan (+5.5) and No. 1 Ohio State vs. No. 5 Texas (-1.5). Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:

Our proven computer model has revealed exact score predictions for each game that can help you formulate spread, money-line and over/under under picks.

Before making any college football picks for those games or others in Week 2, be sure to see them all.

The model simulates every FBS game 10,000 times. It is on a 33-20 run on top-rated CFB money-line picks since the 2024 season, and it has been upgraded for the 2026 season to even better factor in the transfer portal!

Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 2 game, and the exact score projections are in. 

One of the score projections from the model in Week 2: Oregon beats Oklahoma State 36-18, making Oklahoma State (+22.5) the better value against the spread. The Under 57.5 is also a strong play as it hits 56% of the time.

The model has also made the exact call on the score for every other game, and it's calling for a double-digt underdog to win outright in Week 2!

So what is the exact score prediction for each Week 2 game, and which double-digit underdog pulls off a shocking upset? ... Join SportsLine now to see who wins and covers every single game, all from the model that is on a 33-20 run on top-rated money line picks since 2024!

Don't miss out: All new SportsLine memberships include Paramount+ Premium -- a $13.99/month value -- for no extra cost! Join now and get it all. 

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Daniel Lewis

Written by Daniel Lewis

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