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College football odds, lines, spreads: Picks, predictions, betting advice for Week 6, 2022 from proven model

The SportsLine Projection Model, which has generated more than $3,100 for $100 college football bettors over the past six-plus years, has revealed its college football picks for Week 6
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It's a big weekend of college football with a trio of Top 25 matchups set for Saturday. The Week 6 college football odds from Caesars Sportsbook list No. 8 Tennessee as a 3-point road favorite at No. 25 LSU, while No. 19 Kansas is a 7-point home underdog against No. 17 TCU. No. 11 Utah, meanwhile, is -3.5 at UCLA. National title contenders will also be on display during the SEC on CBS doubleheader with No. 2 Georgia (-28) hosting Auburn at 3:30 p.m. ET and No. 1 Alabama (-24) welcoming Texas A&M at 8 p.m. ET. 

Before making any college football picks for those games or others in Week 6, be sure to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

Now, it has studied the latest college football odds from Caesars (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for Week 6 of FBS college football, and the results are in. 

One of the college picks the model is high on in Week 6: Auburn easily stays within the 28-point spread against No. 2 Georgia in that 3:30 p.m. ET SEC on CBS matchup. The Bulldogs have been shaky the past couple of weeks, not even coming close to covering against Kent State or Missouri. The model says this number is too high against the Tigers and it is projecting Auburn to cover almost 70% of the time. 

Another prediction: No. 7 Oklahoma State (-9) rolls Texas Tech and easily handles this two-score spread in a 3:30 p.m. ET matchup in Stillwater. The Cowboys surpass 40 points in the simulations, helping them cover more than 70% of the time.

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for a Top 25 team to go down HARD in an outright upset! 

So which college football teams should you back this week? And which Top 25 favorite goes down HARD? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned more than $3,100 in profit on top-rated ATS picks over the past six-plus seasons!

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SportsLine Staff

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