The No. 10 Clemson Tigers (5-1) will try to stay on track for a College Football Playoff spot when they host the Virginia Cavaliers (4-2) on Saturday afternoon. Clemson was blown out by then-No. 1 Georgia in its season opener, but it has rattled off a five-game winning streak since then. Virginia had its two-game winning streak snapped in a 24-20 loss to Louisville last week. 

Kickoff is set for noon ET on Saturday at Memorial Stadium. Clemson is favored by 21 points in the latest Clemson vs. Virginia odds, while the over/under is 57.5 points, per SportsLine consensus. Before entering any Virginia vs. Clemson picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 12-5 on all top-rated picks over the past three weeks of this season. Anyone who has followed it has seen strong returns.

The model has simulated Clemson vs. Virginia 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Clemson vs. Virginia? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.