Cavaliers vs. Raptors odds, line: Proven model reveals NBA picks for Game 5 matchup on Wednesday, April 29

The Raptors vs. Cavaliers series in the first round of the NBA playoffs 2026 is down to a best-of-three as it is 2-2 entering Wednesday's Game 5. The fourth-seeded Cavs (52-30) won the first two contests at home before dropping the two in Toronto. The fifth-seeded Raptors (46-36) are looking to end a streak of four straight road defeats, all coming by double-digits. Toronto swept the regular season series, 3-0, including two wins in Cleveland.

Tip-off is at 7:30 p.m. ET from Rocket Arena in Cleveland. The latest Cavaliers vs. Raptors odds from FanDuel Sportsbook have the Cavs as 8.5-point favorites, while the over/under for total points scored is 215.5.

Before making any Raptors vs. Cavaliers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the second full week of the 2026 NBA playoffs on a sizzling 25-9 roll (74%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Cavaliers vs. Raptors 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits well over 50% of the time!

Who wins Raptors vs. Cavs, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 25-9 roll on top-rated NBA picks!