Butler vs. Creighton odds, line, spread: Proven model reveals college basketball picks, predictions for Jan 26, 2022

After back-to-back Big East road losses to ranked teams, Creighton has bounced back with two consecutive wins. The Bluejays continue conference play in a Wednesday night road game against a Butler side that has lost four straight. Game time at Hinkle Fiedhouse is set for 6:30 p.m. ET, where the Bulldogs are 6-4 this year. Creighton last played Butler in the opening round of last season's Big East tourney, where they took a decisive 87-56 win.

The Bluejays are favored by 2.5 points in the latest Butler vs. Creighton odds from Caesars Sportsbook, and the over-under is set at 125.5. Before you make any Creighton vs. Butler picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Butler vs. Creighton 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Butler vs. Creighton? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!