Brewers vs. Tigers odds, line, prediction: 2026 MLB picks for Thursday, April 23 from proven model

The Milwaukee Brewers and Detroit Tigers conclude a three-game series on Thursday afternoon. The two teams have split the first two games of the series. Milwaukee (13-10) won Tuesday's opener before dropping Wednesday's contest, and the Brewers are looking to win the series and make it three won series in a row. Detroit (13-12) is looking for its third series win in four series, with the other being a two-and-two split against Boston.  Brandon Sproat (0-1, 6.88 ERA) will start for the Brewers, countered by Detroit's ace Tarik Skubal (3-2, 2.08 ERA).

First pitch is at 1:10 p.m. ET from Comerica Park in Detroit. The latest Brewers vs. Tigers odds list Detroit as the -221 favorite on the money line (risk $221 to win $100). The over/under for total runs is 7.

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The model has simulated Brewers vs. Tigers 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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