Blue Jays vs. Rays odds, line, prediction: 2026 MLB picks for Wednesday, May 6, from proven model

American League East contenders face off in a Wednesday MLB matinee, as Junior Caminero and the Tampa Bay Rays host Vladimir Guerrero and the Toronto Blue Jays. The Rays are in second place in the AL East, just behind the surging New York Yankees. The Blue Jays are in third as they hope to get back to the World Series. Patrick Corbin (1-0, 3.65 ERA) goes for Toronto, while Shane McClanahan (3-2, 3.10) takes the ball for Tampa. 

First pitch from Tropicana Field in Tampa is set for 1:10 p.m. ET. Tampa is a -139 favorite (risk $139 to win $100) in the latest Blue Jays vs. Rays odds, while Toronto is at +117 (wager $100 to win $117 in profit). The over/under for total runs is 7.5. 

Before making any Blue Jays vs. Rays picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times, and is coming off a 5-0 week on top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.   

The model has simulated Blue Jays vs. Rays 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

Who wins Rays vs. Blue Jays, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the Blue Jays vs. Rays money line you should be all over, all from the model that went 5-0 on top-rated MLB picks last week!