Astros vs. Twins odds, picks: Advanced computer MLB model releases selections for Saturday matchup

The Houston Astros visit the Minnesota Twins for an American League tilt at 2:10 p.m. ET on Saturday. Minnesota is listed as a -120 favorite (risk $120 to win $100) at Caesars Sportsbook, while the over/under is set at 7.5 (see up-to-date odds for every game this week on our MLB odds page). 

Before making any Astros vs. Twins picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anybody who has followed it has seen profitable returns!

The model knows the Astros have a quality starting pitching option with Luis Garcia. The 26-year-old posted a 3.72 ERA in 2022, including a 1.86 ERA after September 1. Garcia also had a 2.85 ERA on the road last season and is comfortable away from Houston.

The model also knows the Twins are in a strong position with Joe Ryan on the hill. He threw six innings of one-run ball in a win over Kansas City to begin the 2023 season. Ryan also had a 3.55 ERA, including a 3.04 ERA at home, in 2022 with a 2.20 ERA over his last five starts of the season.

Now, it has set its sights on Astros vs. Twins. We can tell you the model is leaning Over the total, and it also says one team has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Astros vs. Twins? And which team has ALL the value on the money line? ... Join SportsLine right now to find out which side of the Astros vs. Twins matchup you should be all over Saturday, all from the model on a roll on MLB picks!