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Injuries haven't derailed Brock Purdy, Christian McCaffrey the San Francisco 49ers, who take a 7-1 record into an NFL Week 10 showdown with Dak Prescott and the Dallas Cowboys. The Niners rolled the Raiders 38-17 last week to rebound from their lone loss of the season. The Cowboys (4-5) have been far more inconsistent but has a Top 10 offense that has scored at least 27 points the last three games. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Kickoff is set for 4:25 p.m. ET from AT&T Stadium in Dallas. The latest 49ers vs. Cowboys odds have San Francisco as a 4-point favorite. The over/under for total points scored is 55.5.
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Now, the model has locked in another confident pick for 49ers vs. Cowboys in the NFL Week 10 2026 matchup.
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