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Week 2 of the 2026 NFL season features 14 Sunday matchups, and NFL bettors are looking for score predictions they can work off of to form spread, total, money-line and prop picks ahead of a massive Week 2 slate. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Some notable NFL spreads on the Week 2 NFL schedule include Bengals vs. Texans (-3, 46.5), Steelers vs. Patriots (-5.5, 41.5), Colts vs. Chiefs (-6.5) on Sunday night and Giants vs. Rams (-7, 48.5) on Monday.
Before you lock in any Week 2 NFL picks, make sure you see what SportsLine's advanced computer model has to say.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
Now, the model has evaluated the latest NFL odds, simulated every snap for Week 2 of the 2026 NFL season, and the results are in.
We can tell you SportsLine's model likes the Dallas Cowboys (-3.5, 50.5) to beat the Washington Commanders, 32-28, at home. The Cowboys have dominated this series recently, winning eight of the last 10 meetings against the Commanders. Washington has dropped eight of its last 10 games overall. In addition, the Commanders are 5-3 against the spread in their last eight games. The model projects Dak Prescott of the Cowboys will throw for 290 yards and 2.3 touchdowns, while Washington's defense racks up 2.28 sacks on average.
In addition, the model is calling for one specific underdog to pull off a SHOCKING upset! Nailing these results is key to making profitable Week 2 NFL picks. You ABSOLUTELY NEED to see who to pick before locking in any Week 2 NFL score predictions!
What are the projected scores for every Week 2 NFL game? And which underdog shocks the NFL? ... Join SportsLine now to get NFL Week 2 score predictions, all from the model on a dominant 53-39 roll!
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Written by Daniel Kohn
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