2026 NFL Week 3 odds, score predictions: SportsLine AI reveals picks for every game
SportsLine AI reveals its NFL picks against the spread, over/under and money line for every NFL game in Week 3
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Early-season injuries have already struck several teams, while others are desperate to get a win as Week 3 of the NFL season features Atlanta at Green Bay on Thursday, 14 games on Sunday and one on Monday. Among Sunday's more intriguing matchups is an AFC North clash between the Cincinnati Bengals and Pittsburgh Steelers (+3.5). The highest O/U of any of the Sunday games is an interconference matchup between the Baltimore Ravens and Dallas Cowboys (52.5) in Brazil. It is one of six interconference matchups in Week 3. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Week 3 ends with a 'Monday Night Football' matchup between the Philadelphia Eagles vs. Chicago Bears (+3.5). The Eagles are coming off a 24-20 win at Tennessee, while Chicago dropped a 9-3 decision to the Minnesota Vikings as Bears quarterback Caleb Williams was carted off the field with a hamstring injury. His status is unknown for the coming week. Sunday's largest spreads include Chiefs vs. Dolphins (+11.5), Chargers vs. Bills (-7), Seahawks vs. Commanders (+6.5) and Jets vs. Lions (-6.5). The smallest spreads in Week 3 include Texans vs. Colts (+2.5), Rams vs. Broncos (+2.5), Panthers vs. Browns (+2.5), Patriots vs. Jaguars (-2.5) and Vikings vs. Buccaneers (+2.5).
Before making any Week 3 NFL picks, be sure to check out the NFL score predictions from the SportsLine's self-learning AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data then quantitatively evaluating the strength of the opponents defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see a 5-star rating on an Over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. It has nailed thousands of 4.5- and 5-star prop picks since the start of the 2023 season! Anyone who has followed it could be WAY UP!
After analyzing every game in Week 3, the AI says the Under hits in the Patriots vs. Jaguars (-2.5, 44.5) matchup as New England wins 20-19 on average.
SportsLine AI has generated against the spread, over/under and money-line picks for every game in Week 3! In fact, the AI has generated several other HIGHLY-COVETED A+ picks! You ABSOLUTELY NEED to see the AI analysis before making any Week 3 NFL bets.
Which NFL bets do you need to make NOW for Week 3? And which must-see NFL picks are worthy of an A+ rating? ... Join SportsLine now to see the top 2026 Week 3 NFL picks, all from the self-learning SportsLine AI that has nailed a COLOSSAL 2,000+ top-rated picks since the start of last season!
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Written by Daniel Kohn
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