Oscar Piastri sits atop the 2025 Formula 1 driver's standings and will be out to earn his eighth win of the season when he takes part in the F1 United States Grand Prix at the Circuit of the Americas in Austin, Texas, on Sunday. The Australian holds a 22-point advantage over Lando Norris of Great Britain. Piastri is looking for his first win since taking the Dutch Grand Prix on Aug. 31, while Piastri will look to get back into the win column for the first time since Aug. 3 at the Hungarian Grand Prix. Both Piastri and Norris are looking to snap Max Verstappen's four-year stranglehold on the Formula 1 season championship.

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Verstappen, who won pole position on Saturday, as well as the sprint, is the favorite at +135. Other favorites include Norris at +185 and Piastri at +360 in the latest 2025 United States Grand Prix odds, from DraftKings Sportsbook. Other favorites are George Russell at +1400, and Charles Leclerc and Lewis Hamilton, both at +2800, with Hamilton being a six-time winner of this race but still seeking his first win of the year. Sunday's race is scheduled to start at 3 p.m. ET from the 20-turn COTA track.

Before making any 2025 United States Grand Prix picks or Formula 1 predictions, you need to see what auto racing insider Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every lap of Formula One action, taking factors such as matchups and statistical trends into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. 

Now, McClure has turned his attention to the Formula 1 United States Grand Prix and just locked in his top picks. 

McClure has also identified his top three drivers for his 2025 F1 United States Grand Prix best bets. He's also high on a huge NASCAR longshot who's going off at 100-1, potentially netting any backer a huge payday!

So who wins the 2025 United States Grand Prix at the Circuit of the Americas in Austin, Texas, and which massive longshot could stun NASCAR? Visit SportsLine now to see the 2025 F1 United States Grand Prix picks and best bets from an F1 insider, and find out.

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