2025 RBC Heritage odds, picks: Golf expert reveals best bets for the weekend

The 2025 RBC Heritage heads for Round 3 Saturday morning at Harbour Town. Justin Thomas is the leader at 12 under and four other golfers are within three shots of the lead. Scott Scheffler (-8) and Collin Morikawa (-7) are among the other big names within striking distance.

Thomas is the is the +200 favorite (risk $100 to win $200) to win heading into the weekend according to the latest 2025 RBC Heritage odds, followed by Scheffler (+400), Russell Henley (+650), Si Woo Kim (+1000) and Tommy Fleetwood (+1000).

Before making any 2025 RBC Heritage picks for the weekend, you NEED to see this PGA Tour best bets from Eric Cohen!

Cohen is an avid golf bettor who correctly predicted the pre-tournament outright winner in seven tournaments over the last two seasons. He correctly identified Aaron Rai at +3300 odds in the 2024 Wyndham Championship, as well as Davis Thompson (2024 John Deere Classic, +2200), Bryson DeChambeau (2024 U.S. Open, +2000), Scottie Scheffler (2024 Players Championship, +550), Rickie Fowler (2023 Rocket Mortgage Classic, +1400), Brooks Koepka (2023 PGA Championship, +2000), and Chris Kirk (2023 Honda Classic, +3500).

Anyone who has followed Cohen's predictions could have seen huge returns in those tournaments! Now, Cohen has studied the leaderboard at the RBC Heritage and revealed his weekend best bets. 

For the RBC Heritage 2025 weekend, Cohen likes Patrick Cantlay, who is tied for 13th at 6 under, to finish in the top five (with ties), a bet that returns +350.

"He's a horse for the course with five top-3 finishes in seven trips," Cohen said. "It's hard to believe that stat is real and also that Cantlay still hasn't won at Harbour Town. Spoiler alert: he's not going to win this week either but he has the potential to go low and stay consistent here. The putter hasn't been great, to the tune of two strokes worse than the field average, but that can easily change over the next two days. Make sure to play this bet with ties (these odds factor in ties) as an outright top-five seems difficult."

Cohen also has locked in four other best bets, including a HUGE longshot who returns around 50-1! You ABSOLUTELY need to see these golf picks before locking in any PGA Tour picks of your own.

So who wins the 2025 RBC Heritage, and which HUGE longshot should you jump on for the weekend? Join SportsLine now to get Eric Cohen's weekend picks, all from the golf expert who has called seven outright winners since 2023!