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2025 college football Week 7 odds, lines, trends: Legendary Vegas expert reveals picks, predictions, best bets

Legendary college football expert Bruce Marshall reveals the top values in the Week 7 lines

ByPublished: Oct 11, 2025 1:19PM UTC . 3 min read

The Week 7 college football schedule has arrived, and there are a pair of top-15 matchups set for Saturday. No. 8 Alabama (-3) takes on No. 14 Missouri, while No. 3 Oregon (-7) faces No. 7 Indiana on CBS and Paramount+.

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Other notable Week 7 college football games include No. 6 Oklahoma vs. Texas (-1.5), with Arch Manning and the Horns looking to rebound after falling to Florida, while OU's John Mateer is now listed as probable (hand) There's also No. 1 Ohio State vs. Illinois (+14.5) and No. 10 Georgia vs. Auburn (+4). Additionally, one of the slimmest college football spreads has Deion Sanders and Colorado as 3-point underdogs versus Iowa State (see more college football lines right here). 

Before making any Week 7 college football bets, be sure to see what legendary college football handicapper Bruce Marshall has to say. 

For years Vegas-based Marshall was synonymous with The Gold Sheet, the famous sports betting newsletter. He has won various handicapping titles and crushed the 2024 college football season, going 64-43 (plus 16.24 units) at SportsLine! 

Now he's studied the Week 7 college football schedule and used his Tech Corner technique to break down every matchup.

One thing we can tell you for Week 7: Marshall likes Missouri (+3.5) to cover against Alabama in a noon ET start on Saturday. He also likes the Over (51.5).

"Alabama romped in this one 34-0 last October, but that was at Tuscaloosa," Marshall said. "Tide are just 2-5 both straight up and spread in their last seven away from Bryant-Denny Stadium. The Tigers are on an 8-2 spread surge since last year's loss (that includes just missing as 44.5 vs UMass), and 7-4 as underdogs since 2023. Mizzou is also on an 8-2 over run since late 2024, and the Bama game last October. Tech edge-Missouri and Over, based on team and totals trends."

Marshall has evaluated every other matchup and he's found a key 12-5 ATS trend you need to know about in Week 7! You ABSOLUTELY need to see who it is before making any college football picks. 

Who should you back in Week 7 of college football, and what alarming trend do you need to know about this week? ... Join SportsLine now to find out, all from the legendary Vegas handicapper who has won multiple handicapping titles and went 64-43 on CFB picks last year!

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